Gynae oncologyFree in the app
Tumour markers
Which marker points where.
Source: RCOG GTG 62 · standard teaching| CA-125 | Epithelial ovarian cancer. Also raised in endometriosis, PID, fibroids, pregnancy, ascites. |
|---|---|
| CA19-9 | Mucinous ovarian, pancreatic or GI cancer, dermoid. |
| CEA | GI primary or Krukenberg. CA-125:CEA below 25 suggests GI origin. |
| AFP | Yolk sac tumour, embryonal, immature teratoma. |
| hCG | Choriocarcinoma, embryonal, GTN. |
| LDH | Dysgerminoma. |
| Inhibin A/B, AMH | Granulosa cell tumour. |
| HE4 | Epithelial ovarian; less affected by endometriosis (used in ROMA). |
A summary for trained clinicians. Always check the full guideline, the patient in front of you and your hospital's protocol. Spotted an error? Tell us.