Gynae oncologyFree in the app
Cervical cancer — treatment by stage
Surgery for early disease, chemoradiation for advanced.
Source: FIGO 2018 · ESGO/ESTRO/ESP 2023 · SHAPE trial| IA1, no LVSI | Cone with clear margins if fertility wanted; otherwise simple hysterectomy. Sentinel nodes only if LVSI. |
|---|---|
| IA2–IB1 low risk (≤2 cm) | Simple hysterectomy plus pelvic node assessment (SHAPE trial). |
| IB1–IIA1 | Radical hysterectomy (open preferred) with sentinel and pelvic nodes. Adjuvant chemoradiation if nodes, parametria or margins involved. |
| Fertility-sparing | Trachelectomy or cone for tumours ≤2 cm with negative nodes. |
| IB3–IVA | Chemoradiation: pelvic RT 45–50 Gy with weekly cisplatin 40 mg/m², then brachytherapy; finish within 50 days. |
| IVB / recurrent | Platinum-paclitaxel ± bevacizumab, plus pembrolizumab if PD-L1 positive. |
Pakistan began single-dose HPV vaccination for girls aged 9–14 in September 2025 (Punjab, Sindh, AJK, ICT first; KP 2026; Balochistan and GB 2027).
A summary for trained clinicians. Always check the full guideline, the patient in front of you and your hospital's protocol. Spotted an error? Tell us.