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Fluids and transfusion
Daily needs, thresholds and major haemorrhage.
Source: NICE CG174 · NICE NG24| Maintenance | 25–30 ml/kg/day water; about 1 mmol/kg/day sodium, potassium and chloride; 50–100 g/day glucose. |
|---|---|
| Frail, kidney or heart disease | 20–25 ml/kg/day. |
| Resuscitation | 500 ml crystalloid over 15 minutes or less, then reassess. |
| Transfusion | Hb below 70 g/L (target 70–90); below 80 with acute coronary syndrome. One unit, then reassess. |
| Major haemorrhage | Red cells and FFP 1:1, then platelets and cryo by results. Tranexamic acid 1 g IV. |
| Targets | Fibrinogen above 2 g/L in obstetrics (1.5 otherwise), platelets above 75, PT/APTT below 1.5× normal, temperature above 36 °C. |
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