GynaePulse
Infections in pregnancyFree in the app

Typhoid — XDR strain

Extensively drug-resistant typhoid in Sindh since 2016.

Source: Euro Surveill 2019 · Pakistan practice
XDR resistanceAmpicillin, co-trimoxazole, chloramphenicol, fluoroquinolones and ceftriaxone.
UncomplicatedAzithromycin (e.g. 1 g daily for 7 days).
Complicated or severeMeropenem IV.
PregnancyAvoid fluoroquinolones. Azithromycin is the only oral option.
PreventionTyphoid conjugate vaccine, safe water.
A summary for trained clinicians. Always check the full guideline, the patient in front of you and your hospital's protocol. Spotted an error? Tell us.