Infections in pregnancyFree in the app
Tuberculosis in pregnancy
First-line drugs are safe.
Source: WHO · CDC 2025- Standard regimen: isoniazid, rifampicin, pyrazinamide and ethambutol for 2 months, then isoniazid and rifampicin for 4.
- Pyridoxine 25–50 mg daily with isoniazid.
- Avoid streptomycin and other aminoglycosides (deafness in the baby).
- Rifampicin reduces hormonal contraception — use an IUD or DMPA.
- Breastfeeding is fine. Baby: BCG and isoniazid preventive therapy if the mother is smear-positive.
A summary for trained clinicians. Always check the full guideline, the patient in front of you and your hospital's protocol. Spotted an error? Tell us.