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Malaria in pregnancy

Vivax is commonest in Pakistan; falciparum is the killer.

Source: WHO 2022
Uncomplicated falciparum, 1st trimesterArtemether-lumefantrine (WHO 2022).
2nd and 3rd trimesterACTs as in non-pregnant adults.
Severe, any trimesterIV artesunate 2.4 mg/kg at 0, 12 and 24 hours, then daily.
VivaxChloroquine, then weekly chloroquine until after birth; radical cure later.
AvoidPrimaquine and tafenoquine in pregnancy and breastfeeding.
Check glucose often — quinine and severe malaria cause hypoglycaemia.
A summary for trained clinicians. Always check the full guideline, the patient in front of you and your hospital's protocol. Spotted an error? Tell us.