Antenatal & maternal medicineFree in the app
Preterm labour & PPROM
Diagnosis, steroids, magnesium, tocolysis.
Source: NICE NG25Diagnosis ≥30 wk
| Cervical length | ≤15 mm = preterm labour likely. |
|---|---|
| Fetal fibronectin | >50 ng/ml positive. |
| ≤29+6 wk | Treat on clinical suspicion. |
Windows
| Steroids | Offer 24+0–33+6; consider 34+0–35+6. |
|---|---|
| MgSO4 | Offer 24+0–29+6; consider 30+0–33+6. |
| Nifedipine | Offer 26+0–33+6; consider 24+0–25+6. |
Prevention
- Previous preterm birth/mid-trimester loss + cervix ≤25 mm at 16–24 wk: progesterone or cerclage
- Vaginal progesterone from 16–24 wk to ≥34 wk
PPROM: erythromycin 250 mg QDS 10 days. No co-amoxiclav. No scalp electrode or FBS before 34 weeks.
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