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Hypertension & pre-eclampsia

Definitions, admission and timing of birth.

Source: NICE NG133
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Definitions

ChronicBefore 20 weeks or on treatment.
GestationalNew ≥140/90 after 20 wk, no proteinuria.
Pre-eclampsiaNew HTN after 20 wk + uPCR >30 mg/mmol (ACR >8) or organ dysfunction.
Severe≥160/110.

Admit pre-eclampsia if

  • Sustained systolic ≥160
  • Creatinine ≥90 µmol/L
  • ALT >70 IU/L
  • Platelets <150 × 10⁹/L
  • Any clinical concern

Timing of birth

GHTN / chronic, BP <160/110Not before 37+0.
PE <34 wkSurveillance; steroids & MgSO4 if birth planned.
PE 34–36+6Surveillance; consider steroids.
PE ≥37 wkBirth within 24–48 h.

After birth

  • BP daily for 2 days, then once days 3–5
  • Treat if ≥150/100; enalapril (nifedipine/amlodipine for Black African/Caribbean women)
  • Stop methyldopa within 2 days
  • Review at 6–8 weeks
Do not use steroids to treat HELLP. Severe PE: limit fluids to 80 ml/h.
A summary for trained clinicians. Always check the full guideline, the patient in front of you and your hospital's protocol. Spotted an error? Tell us.