GynaePulse
Antenatal & maternal medicineFree in the app

Intrahepatic cholestasis (ICP)

Itch without rash + raised bile acids.

Source: RCOG GTG 43 (2022)

Bile acids

Mild 19–39Birth by 40 weeks.
Moderate 40–99Birth 38–39 weeks.
Severe ≥100Birth 35–36 weeks.
Ursodeoxycholic acid does not improve outcomes — not routine. Recheck LFTs/bile acids 6 weeks after birth.
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