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Puberty problems

Too early, too late, and Tanner staging.

Source: Standard teaching
Precocious pubertySigns before 8 years. Central: mostly idiopathic in girls. Peripheral: ovarian cyst or tumour, McCune-Albright, CAH.
Work-upBone age, LH/FSH (GnRH test), pelvic scan, brain MRI. Central: GnRH agonist.
Delayed pubertyNo breasts by 13, or no periods by 15 (or 3 years after breasts).
Low FSH/LHConstitutional delay, low BMI, Kallmann, pituitary disease.
High FSH/LHTurner syndrome, premature ovarian insufficiency.

Tanner breast stages

B1Prepubertal.
B2Breast bud (thelarche, 8–13 years).
B3Breast and areola enlarge together.
B4Areola forms a secondary mound.
B5Adult contour.
A summary for trained clinicians. Always check the full guideline, the patient in front of you and your hospital's protocol. Spotted an error? Tell us.