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Male factor and fertility preservation

Always test the man.

Source: WHO 2021 · NICE NG257

Semen lower limits (WHO 2021)

Volume1.4 ml
Concentration16 million/ml
Total count39 million
Progressive motility30%
Normal forms4%
  • Repeat an abnormal test after 3 months (sooner if no sperm).
  • Azoospermia: FSH, LH, testosterone, karyotype, Y-microdeletion, CFTR. Surgical sperm retrieval with ICSI.
  • Fertility preservation before chemo or pelvic radiotherapy: egg or embryo freezing, ovarian tissue freezing, ovarian transposition.
A summary for trained clinicians. Always check the full guideline, the patient in front of you and your hospital's protocol. Spotted an error? Tell us.